Our experimental results demonstrate that the ranking algorithm-based classifiers provide plans that enhance infection rate control, especially with increased action budgets for small networks.

In this study, we investigate the under-explored intervention planning aimed at disseminating accurate information within dynamic opinion networks by leveraging learning strategies. Intervention planning involves identifying key nodes (search) and exerting control (e.g., disseminating accurate/official information through the nodes) to mitigate the influence of misinformation. However, as the network size increases, the problem becomes computationally intractable. To address this, we first introduce a ranking algorithm to identify key nodes for disseminating accurate information, which facilitates the training of neural network (NN) classifiers that provide generalized solutions for the search and planning problems. Second, we mitigate the complexity of label generation--which becomes challenging as the network grows--by developing a reinforcement learning (RL)-based centralized dynamic planning framework.

Our experimental results demonstrate that the ranking algorithm-based classifiers provide plans that enhance infection rate control, especially with increased action budgets for small networks.

This study presents an integrated approach to understanding epidemic dynamics through a stochastic spatio-temporal simulation model on a multiplex network, blending physical and informational layers. The physical layer maps the geographic movement of individuals, while the information layer tracks the spread of knowledge and health behavior via social interactions. We explore the interplay between physical mobility, information flow, and epidemic outcomes by simulating disease spread within this dual-structured network. Our model employs stochastic elements to mirror human behavior, mobility, and information dissemination uncertainties. Through simulations, we assess the impact of network structure, mobility patterns, and information spread speed on epidemic dynamics. The findings highlight the crucial role of effective communication in curbing disease transmission, even in highly mobile societies. Additionally, our agent-based simulation allows for real-time scenario analysis through a user interface, offering insights into leveraging physical and informational networks for epidemic control. This research sheds light on designing strategic interventions in complex social systems to manage disease outbreaks.

The disease has been plaguing the endangered marsupials since the 1990s. Breakthroughs, discoveries, and DIY tips sent every weekday. The first vaccine to protect endangered koalas from chlamydia has officially been approved in Australia. The vaccine was developed by the University of the Sunshine Coast's (UniSC) veterinary medicine division in eastern Australia and is another step towards ensuring the survival of the marsupial. The team spent over a decade developing the vaccine to protect the animals from the disease, which can cause urinary tract infections, blindness, infertility, and in some cases, death.

Methicillin-resistant Staphylococcus aureus (MRSA) is a critical public health threat within hospitals as well as long-term care facilities. Better understanding of MRSA risks, evaluation of interventions and forecasting MRSA rates are important public health problems. Existing forecasting models rely on statistical or neural network approaches, which lack epidemiological interpretability, and have limited performance. Mechanistic epidemic models are difficult to calibrate and limited in incorporating diverse datasets. We present CALYPSO, a hybrid framework that integrates neural networks with mechanistic metapopulation models to capture the spread dynamics of infectious diseases (i.e., MRSA) across healthcare and community settings. Our model leverages patient-level insurance claims, commuting data, and healthcare transfer patterns to learn region- and time-specific parameters governing MRSA spread. This enables accurate, interpretable forecasts at multiple spatial resolutions (county, healthcare facility, region, state) and supports counterfactual analyses of infection control policies and outbreak risks. We also show that CALYPSO improves statewide forecasting performance by over 4.5% compared to machine learning baselines, while also identifying high-risk regions and cost-effective strategies for allocating infection prevention resources.